Your relatives or friends may take them to cope with asthma symptoms. Someone of your surrounding can deny consuming them, but easily get crazy or even angry with no reason. In addition, famous athletes try to keep secret the fact of taking them otherwise they risk to be caught with the blood test and, accordingly, disqualified. It’s all about steroids. In this article, we’ll give answers to such questions as “what are steroids”, “what do steroids do”, etc.
What Are Steroids – Knowledge From the Beginning
Steroid is an organic compound with special molecular configuration, containing four rings. Its examples include: dietary cholesterol, the “chief” male (testosterone), female (estradiol) sex hormones, and dexamethasone (an anti-inflammatory drug).
Steroids function in two main directions: some of them (like cholesterol from cell membranes) modify membrane fluidity; many are presented by signaling molecules aimed at activating special receptors.
What Do Steroids Do and How Are They Classified
There are the following groups of steroid hormonal molecules distinguished on the basis of their functions:
1.Progestogens (progestagens or gestagens). They control uterus endometrium cyclical changes as well as guarantee pregnancy maintaining.
2. Corticosteroids (corticoids). Among them are:
- aldosterone, whose aim is to regulate blood pressure;
- cortisol – this glucocorticoid suppresses the immune system.
3. Androgens. They include testosterone, dehydroepiandrosterone (DHEA), androstenedione, androstenediol, androsterone, dihydrotestosterone (DHT). Testosterone (“the king”) provides both developing and maintaining secondary sexual characters in men.
4. Estrogens. These are feminine sex hormones, which perform the same function in women’s bodies as testosterone in men’s ones.
Natural and synthetic steroids with a similar structure act in different physiological ways, therefore they are widely used in medicine as anti-inflammatory, cardiac, contraceptive and other remedies. For example, Clomid for women is an infertility medication.
How Do Steroids Work – Effect on Your Body
Often steroids and their metabolites, affect our body similarly to signaling molecules. Cell membranes contain both steroids and phospholipids. Membrane fluidity is significantly decreased due to cholesterol (a steroid precursor). Steroids, like lipids, are considered natural stores, where much energy is concentrated. However, these energy sources are not typical. They normally tend to metabolize and excrete in mammals.
How do steroids work? Diversely. For instance, corticosteroids aim to decrease inflammation and reduce immune system activity. Anabolics work by increasing muscle mass. Drugs, based on oestradiol affect the female reproductive system.
How to Get Steroids?
Many persons are interested in how to get steroids. You can purchase them as medicines only if you have appropriate medical conditions (certain diseases).
Sometimes, anabolics are prescribed to patients, who suffer from anemias. They’re also appropriate tools for men, who are not able to produce a sufficient quantity of testosterone. Besides, physicians usually prescribe corticosteroids, which function as swelling reducers.
It’s worth noting that corticosteroids do not damage our health (when used properly), unlike anabolic steroids ’cause they are often misused.
You’ll never meet a qualified doctor, who advises young and healthy people to consume anabolic steroids, especially with the aim to build huge muscles. If a person needs to take them for other purposes, a healthcare professional’s prescription is compulsory. Its absence makes buying and consuming AAS illegal in most countries.
Where to Get Steroids?
You can buy drugs, which contain steroidal substances, in brick-and-mortar chemist’s shops or using online services on the Internet. Regarding “juice”, if you want to buy it, you should be aware that in most countries it’s available only on the black market.
There are two sources of stuff on illegal black market. It can be smuggled on the border from those countries, which do not forbid using steroids and where they can be sold legally. Another source is underground labs, where imported hormones are secretly manufactured into anabolics.
What Are Anabolic Steroids and How They Work?
The kind of steroids you definitely have heard most about is anabolic steroids. Their activity is almost identical to men’s sex hormones. That is why doctors tend to prescribe them if they need to cure late puberty and steep musculature downfall in individuals, who suffer from such dangerous illnesses as cancer or AIDS. Unfortunately, many athletes, even famous ones, use these products illegally and in an uncontrolled way for the purpose of growing massive muscles and achieving a big strength to get an unfair advantage in competitions.
So, what are anabolic steroids? Anabolic-androgenic steroids (AAS) are meds, which imitate testosterone and DHT effects. Due to them the formation of bodily protein gains momentum, which results in hypertrophy of the muscle tissue (this process is called anabolism in medical science), so they are a mainstream phenomenon in musclebuilding. The action of AAS is tritely divided into two directions: anabolic & androgenic effects:
1. Anabolic effect is manifested in intensifying protein production and hypertrophy of musculature.
2. Androgenic effects are resulted in masculinization (development of male traits in girls) and virilization (manifestation of male traits in men and in women on steroids). Many unwanted effects of these medicines are associated with androgen activity. These are acne, seborrhea and dandruff, body hair growth, baldness, prostatic hypertrophy, testicular atrophy, etc.
Why Are Steroids Illegal?
When people ask a question why are steroids illegal, they mean AAS, since corticosteroids and some other drugs are completely accessible in almost all countries if a person has certain medical reasons.
Control legislation differs significantly from one country to another. As a rule, most states forbid steroid circulation without necessary prescription. For instance, the USA government classifies steroids into 3 types in the Controlled Substances Act of 2004. All the steroids are illegal when used without doctor‘s prescription. However, it is quite difficult to get a necessary prescription, because it can’t be given without any purposes. The valid medicinal argument, such as low testosterone disease (hypogonadism) or strict androgen suppression (andropause) should exist.
If you’ve managed to get a prescription, the steroid dosage, specified in it is less than that for growing muscle mass. Besides, in some occasions, athletes have to use veterinary drugs, because a significant part of steroids, which people can consume, is still not produced.
Few countries (Mexico, Thailand, and Moldova) allow purchasing steroids without a prescription. Nevertheless, even the complete legality of these drugs here doesn’t mean you can freely import them to your native country.
What Do Anabolic Steroids Do?
Let’s find the answer to the question what do anabolic steroids do. These drugs (such as stanozolol pills) are characterized by specific anabolic activity. Anabolism is the biosynthesis of various metabolic products (proteins, fats, carbohydrates), unlike catabolism, which is the other metabolism constituent that causes the decay (degradation). Both processes are primarily carried out by enzymatic ways. The most distinctive feature of these substances is their ability to promote protein synthesis in the body and cause nitrogen excretion decrease. Anabolics also help the body to fix calcium (Ca) in bone tissues. Clinically, their effect is manifested by augmenting appetite, enhancing performance, general condition, increasing weight of the body.
How Do Anabolic Steroids Work in the Body?
After falling into the bloodstream, AAS molecules are spread throughout the whole body, where they start reacting with cells of skeletal muscle, sebaceous glands, hair pouches, some brain areas and certain endocrine glands. These substances decompose in fats (are fat-soluble). This allows them to penetrate the fat-made membranous. There, AAS send signals to the nucleus androgen receptors and the cytoplasm. Triggered androgenic receptors communicate inside the cell nucleus, resulting in modifications in gene expression or promotion of the processes that “mail” signals to other areas of the cell. As a result, it leads to enhancing of all kinds of nucleic acid production and creation of new molecules of protein. It is the answer to “how do anabolic steroids work” question.
Such meds as Cabergoline are often used to avoid side effects of anabolic drugs.
The anabolic meds’ effect on the fast bulking is provided by:
- better protein synthesis;
- shortening of recovery periods after trainings;
- catabolic hormones’ (cortisol, etc.) effect decreasing;
- displacement of cell differentiation towards the muscle ones, suppression of the formation of fatty deposits;
- enhancing of metabolic reactions, which leads to fat cells break down;
- strong muscular memory activation.