Mesterolone (also known as Proviron) is a drug of a steroid nature. It has moderate androgenic properties. The drug can inhibit aromatase thereby maintaining estradiol at reference values. However, this effect is weaker in comparison with some medicines such as Clomiphene citrate. The drug is widely distributed in bodybuilding because it increases the effectiveness of other steroids in the cycle. This is caused by a decrease in the level of sex hormone-binding globulin, which stimulates an increase in the free testosterone.
Buy Mesterolone: Use and Effects in Bodybuilding
The medicament is mainly used by athletes during cycles as an auxiliary remedy to increase the level of free testosterone, thereby enhancing protein synthesis and stimulating the growth of dry muscle mass. It can also be used during cycles with trenbolone, nandrolone, and other anabolic steroids to prevent the effect of reducing libido against the background of taking these medications. It can reduce the manifestations of gynecomastia.
The use of this drug in PCT (post cycle therapy) does not make sense for athletes whose endogenous (natural) testosterone level is higher or keeps at high reference values. For sportsmen with a low level of endogenous testosterone, taking this medication may be advisable. The usual dosage is 50-100 mg daily or every other day, depending on the rate of athletic performance of a sportsman.
If 50 mg is chosen, then athletes take 25 mg (half a pill) in the morning and another 25 mg (half a pill) at night. If 100 mg dosage is chosen, athletes take 50 mg (1 tablet) in the morning and 50 mg (1 tablet) at night.
Steroid Use for Medical Purposes
Patients can buy Mesterolone and use it for medical indications. This drug improves the quality of sperm and increases the quantity of spermatozoa. It also compensates for the inadequacy of producing male sex hormones, having a positive effect on the development of male sexual organs and secondary sexual characteristics, improves sexual desire and erectile function, and has anabolic properties. In such cases, patients take 25 mg 1-3 times a day.
According to some scientific reports, the product can be used as an antidepressant. In one study (Vogel W, Klaiber EL, Broverman DM., J Clin Psychiatry, 1985), amitriptyline was compared with this medication. Both remedies showed good results — improved mood in patients. However, Mesterolone proved to be less toxic to the human body with fewer side effects.
Possible Side Effects of the Drug
The medication can cause the following side effects:
- liver dysfunction;
- hypertrophy of the prostate;
- hair loss;
- oily skin;
- infertility or deteriorating of reproductive function.
This medical remedy has a high safety profile and almost no adverse events if athletes do not exceed the dosage. Side effects may occur when juicers use dosages over 200 mg daily. The derivative of this drug is dihydrotestosterone, and therefore in high dosages, it negatively affects the formation of new hair follicles and increases the risk of developing prostate hypertrophy. Therefore, for the prevention of such events periodic testing of the prostate gland is recommended during the use of the medication.
Mesterolone from India — an Effective Generic Drug
It can be used to treat certain diseases (androgen deficiency, infertility due to hypogonadism, etc.) However, in the United States, Mester is illegal, as it belongs to anabolic steroids and is often used by athletes as a doping. However, in some countries it is legal. Versions of the drug produced by Indian companies are very popular. India is the largest producer of generic drugs in the world. Indian meds have low price as their manufacturers use ready-made chemical formulas for the production of generic drugs. One such medication is Provironum 25mg Tab, which is produced by the Indian company Zydus Cadila Healthcare Ltd. This Mesterolone version from India is available in packs containing 10 tablets. According to Medindia and search data, other brands include:
- E-Gen (Tosc International Pvt);
- Ethinorm-E (Bennet Pharmaceuticals Ltd.);
- Lynoral (Organon);
- Mestilon (Uni Sankyo Ltd.);
- Progynon C (Zydu);
- Provimed (Balkanpharmaceuticals);
- Provibol (Alpha Pharma);
- Restore (Micro Labs Ltd);
- Mesone (West-Coast);
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