Progesterone deficiency is a fairly common reason that couples encounter when planning a child, and many women experience during pregnancy. For the treatment of progesterone insufficiency, you can use vaginal forms of progesterone meds. These forms are called suppositories. How to use progesterone suppositories? What side effects can they cause? In this article, you will find the answers to these and other questions.
What are progesterone suppositories?
Suppositories containing progesterone are prescribed during pregnancy planning to prepare the inner wall of the uterus for fixing a fertilized egg on it. During pregnancy, it is administered with the purposes of promoting thickening of the endometrium and the proliferation of the system of blood vessels feeding the embryo. The main task of progesterone suppositories is the preparation of a female reproductive system for pregnancy and the prevention of miscarriage. Do not use progesterone suppositories if you are pregnant (unless the medication is part of the fertility improvement treatment, in such cases it can be used in early pregnancy, as prescribed by the doctor).
Progesterone suppository instructions – what should you consider before using the drug?
According to progesterone suppository instructions, you cannot use this medication if you have or have had an allergy associated with synthetic progesterone. Also, before the administration of the medicine, you need to tell your doctor about the following facts:
– stroke, circulatory problems in the past or at the present time;
– breast cancer in the past or at the present time;
– bleeding in the vagina;
– severe hepatic diseases;
– any kind of food allergy (this is due to the fact that suppositories can contain vegetable oils that can cause an allergic effect);
– if you recently had an ectopic pregnancy or an incomplete abortion.
If the above conditions (diseases) are currently observed, the medication is contraindicated to you.
In addition, you should inform your medical expert if you suffer from high blood pressure, kidney disease, asthma and depression. This will help the doctor to determine whether the medication is safe for you.
How to use progesterone suppositories properly?
Here is how to use progesterone suppositories. First of all, it should be noted that it is necessary to familiarize yourself with the instructions to a certain medication before using it. If you have any questions, you can consult your doctor or pharmacist. Do not use suppositories in smaller (and especially in larger) quantities than prescribed by your doctor and indicated by the instructions for the medication.
Also, you should not take the medication orally. It is intended exclusively for vaginal use.
How to insert a suppository? The suppository should be inserted directly into the vagina, using the applicator, which is attached to the product. This applicator is intended only for single use, so after intravaginal administration of the suppository, it must be discarded.
Vaginal suppositories are supplied in special containers. The pharmacist can show you how to get a suppository from the container properly, adhering to the rules of hygiene. Do not keep the suppository in your hands for too long, as it can begin to melt. If the medicine causes dizziness and severe drowsiness, use it before going to bed. Most likely, in the morning, there will be no trace from these side effects. Vaginal suppositories based on progesterone should be stored in the refrigerator. Do as indicated in the instruction.
What to do if you missed the dosage of the medication? You can apply the missed dose if there is still a lot of time before the next administration of the suppository according to the schedule prescribed by the doctor. If you are approaching the time for a new dosage, skip the missed one. Do not use an increased dosage of the suppository to compensate for the deficiency. If you missed two or more medication administrations, call your health care provider to find out what to do in your case.
What to do in case of an overdose? Usually, an overdose does not cause serious side effects. Call an ambulance if you see that someone accidentally swallowed a suppository.
How is the drug withdrawn? The drug is withdrawn gradually, according to the doctor’s recommendations. For this, the dosage is gradually reduced weekly. But if the symptoms of a threatening miscarriage appear again in the form of bleeding, pulling pain in the lower abdomen, you will have to return to treatment. Otherwise, a miscarriage can happen. It is unacceptable to abruptly cancel the drug, because it can provoke an abortion.
An analogue of suppositories is Duphaston. It is available in the form of tablets for oral administration. Unlike suppositories, it usually does not have a sedative effect, so some doctors prefer to prescribe Duphaston. Use of medicines in the form of suppositories or tablets is currently preferable to injections. Injections of oil solutions are very painful and require special skills while a woman can apply candles herself. It should be noted that these medicines are not available over the counter, they can only be purchased if there is a prescription issued by a licensed physician.
Contraindications and possible side effects
Vaginal suppository is usually contraindicated in case of:
- malignant tumors of the breast and genital organs;
- bleeding from the genital tract, the cause of which has not yet been identified;
- increased sensitivity to the constituents of the medicine (soy and peanut butter).
Taking the drug orally is prohibited if a woman has: severe disorders of the liver; predisposition to thrombosis and thrombophlebitis (increased blood clots, accompanied by inflammation of the veins in places where they are blocked by thrombi).
If a woman does not end the period of lactation, it is recommended to interrupt the breastfeeding at the time of taking the drug.
Artificial progesterone should be taken with caution if a woman has:
- some disorders of the cardiovascular system;
- chronic renal failure;
- bronchial asthma;
- depressive conditions;
- hyperlipoproteinemia (excess lipoproteins and / or lipids in the blood).
A few hours after taking progesterone suppositories, side effects may occur. They are drowsiness, which turns into dizziness (we have mentioned it above). Allergic reactions to the drug are possible. Other progesterone suppositories side effects include pain during urination, signs of depression (mood jumps, reluctance to do anything, etc.), vision problems, impaired liver function and some other unwanted reactions.
Many other medications may interact negatively with progesterone suppositories. If you are taking any medication (as well as OTC supplements and even herbs), tell your doctor about it.
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