The balanced concentration of hormonal signaling molecules and other substances is the necessary pre-condition for healthy operation of the human body. Excess testosterone in men is just as perilous as its deficiency.
Testosterone (T hormone) is one of the most important male hormones, needed for the development of secondary sexual characteristics. It penetrates target cells and metamorphoses into dihydrotestosterone (DHT, 5α-dihydrotestosterone, androstanolone, or stanolone). Deficiency of T hormone may cause a decrease in libido, infertility, and the development of a female figure. The lack of this hormone promotes baldness.
When testosterone is low, there is an overabundance of female hormones in the male organism. Elevated T may lead to insomnia, intemperance, and tiredness. Both conditions have a negative impact on men’s health, so they cannot be left untreated.
High Testosterone Causes — When Does the Hormone Increase?
High T levels may be caused by:
- Cushing’s disease (increased secretion of adrenocorticotropic hormone);
- testicular tumors (malignant and benign);
- abnormal growths in the pituitary gland;
- congenital adrenal hyperplasia (CAH);
- androgen insensitivity syndrome (AIS);
- taking certain medications including steroids for sale, such as testosterone pills, therefore, think twice before you buy Mesterolone, for example.
Other high testosterone causes include some types of cancer and hereditary diseases.
High Testosterone Symptoms in Males
Manifestations of this condition may be varied in nature. High testosterone levels are most often detected in professional bodybuilders who use the “juice” to build muscle.
The main signs of high testosterone in men:
- regular headaches;
- lack of self-preservation;
- liver conditions;
- abnormal heart rate (“fluttering”);
- cardiovascular system disorders;
- difficulty sleeping at night;
- excessive body hair;
- deterioration of urination.
Bladder irritation is often accompanied by prostate enlargement. High T may also cause blood clotting leading to thrombi and heart attacks.
The worst consequence of T overabundance is the reduction of the testicles’ functionality and even their atrophy, which can lead to the inability to conceive a child. These consequences may occur in cases of severe abuse of anabolics, such as Methenolone.
If a man notices at least one of the high testosterone symptoms, he needs to contact a medical practitioner immediately who will undertake a rigorous diagnosis to identify the causes and features of the condition. The sex hormone binding globulin (SHBG) test may also be used. The concentration of this globulin depends on several factors:
- sex (male or female);
- liver condition;
- estrogens and androgens rates;
- adrenal function;
- thyroid condition.
A venous blood sample is taken. Beforehand, the patient should rest quietly for an hour without any cigarette smoking. Normal SHBG concentrations in adult males are 10-57 nanomoles per liter (nmol/L). Low globulin means that testosterone levels are elevated.
Besides SHBG, a testosterone level test is also undertaken. According to WebMD, for the age group 19 to 49, normal testosterone rates range from 249 to 836 nanograms per deciliter (ng/dL). Older males should have 193 – 740 ng/dL.
Treatment of High Testosterone in Men
If the diagnostic test confirms the doctor’s assumptions, then relevant therapy is prescribed.
Persistent sexual appetite, anger attacks, and irritability can be conquered simply by stopping the use of meds contributing to the buildup of muscle mass.
How can a man overcome too much testosterone? Proper therapy should include 4 main components:
Diet. Eat the right food, in particular, raw fruits and veggies, avoid trans fats, energy drinks, and other potentially harmful products.
Moderate physical activity. Take regular exercise, long walks and outdoor running favorably affect T levels.
Surgical intervention. This method is the only way to eliminate adrenocortical adenoma. In cases of benign tumors, outcomes following surgery are usually positive. Leydig cell tumor (interstitial cell tumor) in early puberty is also usually treated by surgical operations. After removal of the tumor, the hormonal background gradually normalizes.
Drug treatment. High testosterone caused by excessive synthesis of androgens and premature puberty, can be treated with hormonal remedies. According to scientific studies and patients’ reviews, these remedies suppress the pituitary gland and diminish the production of gonadotropins (LH and FSH).
High Testosterone Diet — Can It Be Harmful?
You have probably heard about high testosterone diets. What does it mean? It is suggested that some foods can significantly increase the testosterone levels in the blood. Potential testosterone-boosting foods include tuna, low-fat milk with vitamin D, egg yolks, fortified cereals, low-fat fortified milk, oysters, shellfish, beef, and beans. However, the diet does not affect testosterone levels directly but improves the general functions of the body due to the high content of vitamins and minerals. If you suffer from high T, you can generally still eat these foodstuffs but not in large amounts.
Signs of High Testosterone in Women & Treatment Methods
In females, testosterone is responsible for bone tissue formation (it prevents osteoporosis), regulation of lean-to-fat ratio, maintaining energy levels, and libido. Increased T in women is diagnosed more often than in men. It is usually designated as hyperandrogenism (hyperandrogenemia). According to Alexiou E, Hatziagelaki E, Pergialiotis V et al. (Hormone Molecular Biology and Clinical Investigation, 2017), hyperandrogenemia is one of the major diagnostic characteristics for polycystic ovary syndrome (PCOS).
The main signs of increased testosterone in women include:
- excessive hairiness;
- androgenetic hair loss in a “Christmas tree” pattern;
- coarser voice timbre;
- thick and oily skin;
- the development of acne;
- “masculine” outline to the female body shape;
- clitoromegaly (macroclitoris), an abnormal enlargement of the clitoris.
In addition to changes in physiology, a woman will also exhibit changes in her behavior — aggressiveness, ambition, aspiration for leadership. She can become addicted to gambling (sports betting) and alcoholic beverages.
Elevated T in females can be caused by tumors, undernourishment, hereditary predisposition, side effects of illicit over-the-counter steroids (such as Anavar and Proviron) and hyperactive cortical adrenal glands. During pregnancy, this condition is considered normal, since this hormone promotes foetal growth in conjunction with other female sex hormones. The highest T rates are observed in the third trimester. It is necessary to monitor its concentration in the blood, because excessive amounts of testosterone may cause pregnancy loss.
Treatment of high testosterone in women may include some medical remedies. Cyproterone (Diane-35, Siterone, Cypron, Ciclamil, Cetoteron) and dexamethasone (Baycadron, Dexacol, Dexalaf) may be prescribed. With this therapy, hormone levels quickly become normal. Dexamethasone can be successfully administered in low doses (E. Vanky, K.Å. Salvesen, S.M. Carlsen, Human Reproduction, 2003).
After the treatment, it is necessary to repeat testing at regular intervals in order to monitor the concentration of the hormone because following cessation of hormone therapy, the reverse effect may be observed. In this scenario, you need to look for the root cause of this disorder.