The balanced concentration of hormonal signaling molecules and other substances in the necessary condition for healthy operation of the human body. Excess testosterone in men is as perilous as its deficiency.
Testosterone (T hormone) is one the most important male hormones, which is needed for development of secondary sexual characteristics. It penetrates target cells and metamorphoses into dihydrotestosterone (DHT, 5α-dihydrotestosterone, androstanolone, or stanolone). Deficiency of T hormone may cause libido decreasing, infertility, and a female outline of the figure. The lack of a hormone provokes baldness.
When testosterone is low, there is an overabundance of female hormones in the male organism. Elevated T may lead to insomnia, intemperance, and tiredness. Both conditions have a negative impact on the men’s health, so they cannot be left untreated.
High Testosterone Causes — When Does the Hormone Increase?
High T levels may be caused by:
- Cushing’s disease (increased secretion of adrenocorticotropic hormone);
- testicular tumors (malignant and benign ones);
- abnormal growths in the pituitary gland;
- congenital adrenal hyperplasia (CAH);
- androgen insensitivity syndrome (AIS);
- taking certain medications (including steroids for sale, such as testosterone pills), therefore, think twice before you buy Mesterolone, for example.
Other high testosterone causes include some types of cancer and hereditary diseases.
High Testosterone Symptoms in Males
Manifestations of this condition may be sundry in nature. High testosterone levels are most often detected in professional bodybuilders who use the “juice” to build muscle.
The main signs of high testosterone in men:
- regular headaches;
- lack of self-preservation;
- liver conditions;
- abnormal heart rate (“fluttering”);
- cardiovascular system disorders;
- difficulty sleeping at night;
- excessive body hair;
- deterioration of urination.
Bladder irritation is often accompanied by the prostate enlargement. High T may also cause blood clotting leading to thrombi and heart attacks.
The worst consequence of T overabundance is worsening the testicles’ functionality and even their atrophy, which can lead to the inability to conceive a child. These consequences may occur in cases of severe abusing of anabolics, such as methenolone.
If a man notices at least one of the high testosterone symptoms, he needs to contact a medical practitioner immediately. He/she performs rigorous diagnosis to identify the causes and features of the condition. Sex hormone binding globulin (SHBG) test may also be used. The concentration of this globulin depends on a number of factors:
- sex (male or female);
- liver condition;
- estrogens and androgens rates;
- adrenal function;
- thyroid condition.
A venous blood sample is taken. Before it, the person should not smoke at least 1 hour and have physical and moral rest. Normal SHBG concentrations in adult males are 10-57 nanomoles per liter (nmol/L). Low globulin means that testosterone is elevated.
Besides SHBG, testosterone level test is performed. It is effective for diagnosis of early-onset puberty, inability to impregnate, testicular and adrenal gland tumors. According to WebMD, for ages 19 to 49, normal testosterone rates range from 249 to 836 nanograms per deciliter (ng/dL). Older male persons should have 193 – 740 ng/dL.
Treatment of High Testosterone in Men
If the diagnostic test confirms the doctor’s assumptions, the relevant therapy is prescribed.
Permanent sexual appetite, anger attacks, and irritability can be conquered simply by stopping the use of meds contributing to the buildup of muscle mass.
How to overcome too much testosterone? Proper therapy should include 4 main components:
- Diet. Eat right food (in particular, raw fruits and veggies), avoid trans fats, energy drinks, and other potentially harmful products.
- Moderate physical activity. Regular exercise, long walks and outdoor running favorably affect T levels.
- Surgical intervention. This method is the only way to eliminate adrenocortical adenoma. In ace of benign tumors, prediction of the course of the disease after the surgery is usually positive. Leydig cell tumour (interstitial cell tumor) in early puberty is also usually treated by surgical operations. After removing the tumor, the hormonal background gradually normalizes.
- Drug treatment. High testosterone caused by excessive synthesis of androgens and premature puberty, can be treated with some hormonal remedies. According to scientific studies and patients’ reviews, these remedies suppress the pituitary gland and diminish the production of gonadotropins (LH and FSH).
High Testosterone Diet — Can It Be Harmful?
You have probably heard about high testosterone diet. What does it mean? It is suggested that some foods can significantly increase the testosterone levels in the blood. Potential testosterone-boosting foods include tuna, low-fat milk with vitamin D, egg yolks, fortified cereals, low-fat fortified milk, oysters, shellfish, beef, and beans. However, the diet does not affect testosterone levels directly. It improves general functions of the body due to the high content of vitamins and minerals. If you suffer from high T, you generally can eat these products but not in large amounts.
Signs of High Testosterone in Women & Treatment Methods
In females, testosterone is responsible for bone tissue formation (it prevents osteoporosis), regulation lean-to-fat ratio, maintaining energy levels, and libido. Increased T in women is diagnosed more often than in fellows. It is usually designated as hyperandrogenism (hyperandrogenemia). According to Alexiou E, Hatziagelaki E, Pergialiotis V et al. (Hormone Molecular Biology and Clinical Investigation, 2017) hyperandrogenemia is one of the major diagnostic characteristics for polycystic ovary syndrome (PCOS).
The main signs of increased testosterone in women include:
- excessive hairiness;
- androgenetic hair loss in a “Christmas tree” pattern;
- coarser voice timbre;
- thick and oily skin;
- the development of acne;
- “masculine” female body shape;
- clitoromegaly(macroclitoris), an abnormal enlargement of the clitoris.
In addition to changes in physiology, a woman also has a change in her behavior — aggressiveness, ambition, aspiration for leadership. She can become addicted to gambling (sports betting) and alcoholic beverages.
Elevated T in females can be caused by tumors, undernourishment, hereditary predisposition, side effects of illicit over-the-counter steroids (such as Anavar and Proviron) and hyperactive cortical adrenal glands. During pregnancy, such a condition is considered normal, since this hormone promotes the fetal growth in combination with other female sex hormones. The highest T rates are observed in the third trimester. It is necessary to monitor its concentration in the blood, because excessive amounts of testosterone may cause pregnancy loss.
Treatment of high testosterone in women may include some medical remedies. Cyproterone (Diane-35, Siterone, Cypron, Ciclamil, Cetoteron) and dexamethasone (Baycadron, Dexacol, Dexalaf) may be used. With this therapy, hormone levels become normal quickly. Dexamethasone can be successfully administered in low doses (E. Vanky, K.Å. Salvesen, S.M. Carlsen, Human Reproduction, 2003).
After the treatment, it is necessary to get tested and monitor the concentration of the hormone regularly, because after stopping hormone therapy, the reverse effect may be observed. In this case, you need to look for the root cause of this disorder.