Modern pharmacology brings us many different opportunities which we all use in our daily lives and routines to make the health corrections we need. One major invention, which everyone should know about, is noted in the corticosteroids group and its different embodiments.
Synthetic cortisol, which mimics the hormone your body makes in your adrenal gland, actively blocks your body from producing substances that cause inflammation. Corticosteroids are used to treat many conditions and diseases such as chronic obstructive pulmonary disorder (COPD for short), multiple sclerosis, asthma, and arthritis.
Today, we are going to uncover more facts about this grouping of medicines and you will gain a full and correct understanding of this medicament’s advantages.
Corticosteroids Definition: The Basis
The first thing to know is that corticosteroids are hormones of the adrenal cortex. They include glucocorticoids and mineralocorticoids. The main glucocorticoids which are produced in the adrenal cortex are cortisone and hydrocortisone and the main mineralocorticoid is aldosterone.
Corticosteroid substances play a massively important role in every human’s body. Glucocorticoids are steroids too and they have effective anti-inflammatory actions. They participate in the body’s regulation and metabolizing of carbohydrates, fats, and proteins. They help control sexual maturation, kidney function, the body’s response to stress, and contribute to the normal course of pregnancy.
Corticosteroids are generally processed by the hepatic system and liver and are excreted with the urine.
Aldosterone (chemical formulae: C21H28O5) is the base regulatory material for sodium and potassium. Under the influence of mineralocorticoids, our bodies keep all the sodium they need and excise the excessive potassium.
Here, we should say some words about the synthetic corticosteroids definition. Synthetic means man-made, or not naturally occurring. One key thing to note is that synthetic corticosteroids, just like the natural ones, have found a wide range of applications in modern medicine.
They can fix the inflammatory process and bring influence to infectious and autoimmune concerns. But, at the same time, they can’t show any influence on the causative agents of the disease. That is, after the end of the drug’s influence, the infectious agent can restart its reaction over and over again. Thus, eczema that shows a positive reaction to a given steroid cream my reappear once treatment with the ointment is ceased.
The long-term use of and wrong doses can be dangerous because corticosteroids may bring about a negative influence on the immune system. Ongoing corticosteroid treatment needs to be followed by a licensed medical professional, such as your local general practitioner.
Inhaled Corticosteroids and Their Role in Medicine
You probably know that inhaled corticosteroids are the golden choice for asthma treatment therapy. Their influence help to destroy one main reason people develop asthma — inflammation.
It is important to understand that inhaled corticosteroids are completely different to the steroids for sale which sports people and bodybuilders use to make their figures strong and well-defined. The corresponding mechanisms of action are not similar and, in fact, the correct dose of steroidal puffers will never bring any odious harm to one’s health.
Inhalable corticosteroids are common in cases when asthma is regular and the ensuing attacks are deemed serious. The drug’s fast reaction to the condition makes them an ideal choice for many people all over the world, in particular, those battling chronic bronchitis.
Depending on your home nation, corticosteroids for asthmatics may be available over the counter or they may require a valid prescription. It’s important to recognize there are several differing options in inhalers and the correct one needs to be prescribed initially.
Corticosteroid Cream and its Features
Unlike inhalers, in most countries, corticosteroid creams, lotions, and ointments are readily available for purchase in pharmacies, chemist shops, and even supermarkets and 7-11s!
Corticosteroid cream today is the base of treatment in many cases when doctors need to build a foundation for the regulation of inflammatory processes. These products act to block the source of the infections and/or autoimmune responses which are the main cause of the inflammation.
Dermatologists utilize corticosteroid creams to treat the symptoms of various dermal (skin) conditions, including but not limited to:
- Skin ulcers
- Nappy rash
- Lichen planus
- Discoid lupus erythematosus
- Seborrhoeic dermatitis
- Extreme cases of incest bites
- Poison Ivy rashes
- Topical corticosteroids cannot cure the underlying issue, only treat the signs of it. Do not use these potions continuously unless directed by your doctor as lasting skin damages may occur with excessive use.
Often, these meds are prescribed in what’s known as fingertip units (FTUs). One unit is from the top of the finger to the first crease.
Corticosteroid Injections in Medicine
The main idea behind corticosteroidal injections is the blocking of inflammatory processes. Modern corticosteroid injections can be the perfect tool to reach the target issue as fast as possible. For example, epidural steroid injections are commonly used to augment the painful condition sciatica in which the sciatic nerve is trapped in the spinal region and is causing heavy inflammation and discomfort.
Most of the time, any steroid injection is delivered locally, that is, in the local area of the pain or inflammation.
With the help of local corticosteroid injections, it is possible to destroy pain in different kinds of tissues other treatments would not reach. For example, within the ligaments of the vagina.
Systematic support for pain and physical issues brought about by sporting endeavors is oft provided by steroids. Olafsen, Nathan P., MD, et al. writing in the Clinical Journal of Sports Medicine note that the injections are tolerated very well and carry little risk of longer term side effects.
Modern medicine even offers the same treatment to dogs, cats, horses, cows, and other domesticated animals. The action is selfsame: the drug influences the direct target of the pain.
Corticosteroid Pills and Sport
There are many kinds of corticosteroid pills, including:
- bethamethasone, (Celestone)
- Prednisone (Prednisone Intensol)
- Prednisolone (Orapred, Prelone)
- Methylprednisolone (Medrol, Depo-Medrol, Solu-Medrol)
- Dexamethasone (Dexamethasone Intensol, DexPak 10 Day, DexPak 13 Day)
- Hydrocortisone (Cortef)
- Fludrocortisone (Florinef)
Many of the above today are recognizable as the next level of the testosterone optimality and efficiency. Some observations show that the use of corticosteroid pills allow users to reach previously unobtainable results up to five times faster. For that reason, many sports persons use them in their training — often outside of the regulatory body’s recommendations, aka “doping.”
Below is a list detailing some of the desirable and profitable effects which may be reached with corticosteroid pills:
- Swift destruction of adipose (fatty) tissues
- Muscular tissue growth
- Increased sexual desire
- Positive effects on local inflammation
- Stamina support and boosting
- Rapid tissue regeneration
Important negative side effects include
- Immune system suppression
- Weight gain
- Blood pressure spikes
- Mood swings
Not all corticosteroid pills are on the WADA (World Anti-Doping Agency) Prohibited List, but some are. The full list can be viewed on their website. Anabolic steroids are more embroiled in doping schemes and scandals than corticosteroids as a rule. This is because anabolic steroids are derivatives of the male sex hormones so may actively boost an athlete’s performance.
They also engender, temporarily at least, the type of physique bodybuilders lust after. As proven by the proliferation of steroid before and after images making rounds on the net.
Corticosteroids Over the Counter
As we mentioned before, the availability of OTC corticosteroids is determined by the laws of the country you’re currently living in. Some of this drug category, for example, mild hydrocortisone mousses are purchasable just about everywhere without a doctor’s prescription. On the converse, strong versions of the tincture may require a script.
Chances are that if you’re seeking corticosteroids for reasons above and beyond treating a valid medical condition, (i.e. you’re looking to profit for sporting reasons) the meds are NOT available over the counter. In which case, the only true option open to you is to make illicit purchases via online pharmacies — a legal grey area rules here and it’s clever to do some independent research into the legality of your intended plans.
Corticosteroids for Sale – Is it Safe?
Yes. Taken as prescribed and not abused, corticosteroids are a safe way to control numerous processes in the body which lead to inflammatory responses. Within the professional sporting arena, corticosteroids are viewed as both friends and foes thanks to their powerful ability to inhibit local pain and their potential to be indexed alongside their anabolic cousins during screening tests. As A. Rotunno of the University of Pretoria notes, controversy surrounds corticosteroids, even when their use if clinically justified.
Buying from a dedicated online retailer offers a few pros that physical stores simply can’t offer. Consumers list the following as top reason why they prefer to frequent online pharmacies:
- A lot of versions of goods
- Fast delivery
- Less bureaucracy pertaining to prescriptions
- Online support
- Anonymous purchasing
- Help choosing the perfect dose
- Significantly more affordable rates.
As we’ve seen, there is no universal corticosteroids definition because this family of medicines includes a lot of different types and forms: injections, pills, inhalable meds, and ointments. They proffer the perfect short-term treatment in cases when inflammation is a troubling symptom of a given disease or injury.
Forming the base of corticosteroids’ popularity is their sweeping applicability to a diverse range of conditions and their quick mechanism of action.